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Chadsvasc risk factors [click on present risk factors]
RISK FACTORS | SCORE |
---|---|
Congestive heart failure | 1 |
Hypertension | 1 |
Age ≥ 75 | 2 |
Age 65-74 | 1 |
Diabetes mellitus | 1 |
Stroke/TIA/thrombo-embolism | 2 |
Vascular disease | 1 |
Sex Female | 1 |
Result | 0 |
Results
CHADSVASC clinical risk estimation. Adapted from Lip et al.
CHA2DS2VASc SCORE | PATIENTS (n=7329) | ADJUSTED STROKE RATE (% year) |
---|---|---|
0 | 1 | 0 |
1 | 422 | 1.3 |
2 | 1230 | 2.2 |
3 | 1730 | 3.2 |
4 | 1718 | 4 |
5 | 1159 | 6.7 |
6 | 679 | 9.8 |
7 | 294 | 9.6 |
8 | 82 | 6.7 |
9 | 14 | 15.2 |
HASBLED clinical characteristic [click on present risk factors]
CLINICAL CHARACTERISTIC | POINTS AWARDED |
---|---|
Hypertension | 1 |
Abnormal liver function | 1 |
Abnormal renal function | 1 |
Stroke | 1 |
Bleeding | 1 |
Labile INRs | 1 |
Elderly (Age >65) | 1 |
Drugs | 1 |
Alcohol | 1 |
Result | 0 |
Results
HASBLED clinical risk estimation. Adapted from Pisters et al.
HAS BLED SCORE |
NUMBER OF PATIENTS |
NUMBER OF BLEEDING |
BLEEDS PER 100 PATIENT YEARS |
---|---|---|---|
0 | 798 | 9 | 1.13 |
1 | 1286 | 13 | 1.02 |
2 | 744 | 14 | 1.88 |
3 | 187 | 7 | 3.74 |
4 | 46 | 4 | 8.70 |
5 | 8 | 1 | 12.50 |
6 | 2 | --- | --- |
7 | --- | --- | --- |
8 | --- | --- | --- |
9 | --- | --- | --- |
Total | 798 | 9 | 1.13 |
Classificaton of AF-related symptoms (EHRA score)
EHRA I | No symptoms |
EHRA II | Mild symptoms; normal daily activity not affected |
EHRA III | Severe symptoms; normal daily activity affected |
EHRA IV | Disabing symptoms; normal daily activity discontinued |
Recommendations
Haemorrhagic risk | Stroke risk | Clinical setting | Recommendations according to EHRA / ESC / EAPCI 2014 consensus document |
---|---|---|---|
Low or moderate (HAS-BLED 0-2) | Moderate (CHA2DS2-VASC = 1 in males) | Stable CAD | At least 4 weeks (no longer than 6 months): triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/day Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC |
High (CHA2DS2-VASC ≥2) | Stable CAD | At least 4 weeks (no longer than 6 months): triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/day< Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC | |
Moderate (CHA2DS2-VASC = 1 in males) | ACS | 6 months: triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/day Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC | |
High (CHA2DS2-VASC ≥2) | ACS | 6 months: triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/day Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC | |
High (HAS-BLED ≥3) | Moderate (CHA2DS2-VASC = 1 in males) | Stable CAD | Up to 12th month: OAC and clopidogrel 75 mg/day Lifelong: OAC |
High (CHA2DS2-VASC ≥2) | Stable CAD | 4 weeks: triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/day Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC | |
Moderate (CHA2DS2-VASC = 1 in males) | ACS | 4 weeks: triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/dayd Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC | |
High (CHA2DS2-VASC ≥2) | ACS | 4 weeks: triple therapy of OAC + aspirin 75-100 mg/day + clopidogrel 75 mg/dayd Up to 12th month: OAC and clopidogrel 75 mg/day (or alternatively, aspirin 75-100 mg/day) Lifelong: OAC |